TCGA-PRAD · 50 ranked genes · over-expressed in tumor, supported by survival / mutation / known-driver evidence
| # | Gene | Composite | Over-expr (log2FC)GDC tumor vs normal | −log10 pGDC | Tumor-specificity vs GTExGTEx healthy tissue | Mutation freqGDC SSM | Survival p (hi-expr)GDC clinical | Known driverintOGen |
|---|---|---|---|---|---|---|---|---|
| 1 | ABCC4 | 17.70 | 1.55 | 8.6 | 4.00 | 0.012 | 4.7e-02 ↓ | Act |
| 2 | COL2A1 | 7.32 | 3.71 | 13.7 | 5.30 | 0.000 | 9.9e-01 ↓ | LoF |
| 3 | SPINK1 | 6.20 | 3.92 | 5.7 | 5.07 | 0.000 | 5.1e-01 ↓ | — |
| 4 | PCAT14 | 5.55 | 2.57 | 13.7 | 5.67 | 0.000 | 2.1e-01 ↑worse | — |
| 5 | CST2 | 5.42 | 3.35 | 15.5 | 5.42 | 0.000 | 8.5e-01 ↓ | — |
| 6 | GPC5-AS1 | 5.30 | 3.55 | 21.1 | 4.52 | 0.000 | 8.8e-01 ↓ | — |
| 7 | PCA3 | 5.27 | 3.26 | 18.8 | 5.84 | 0.000 | 3.8e-01 ↓ | — |
| 8 | B3GAT1-DT | 4.75 | 2.02 | 24.9 | nan | 0.000 | 4.4e-03 ↑worse | — |
| 9 | SNORD104 | 4.71 | 2.08 | 15.1 | 6.60 | 0.000 | 3.3e-01 ↑worse | — |
| 10 | B3GNT6 | 4.44 | 3.31 | 16.5 | 4.26 | 0.000 | 4.2e-01 ↓ | — |
| 11 | SNORD6 | 4.21 | 1.00 | 7.9 | 3.33 | 0.000 | 7.4e-03 ↑worse | — |
| 12 | TFF3 | 4.17 | 2.55 | 8.1 | 6.06 | 0.000 | 7.3e-01 ↓ | — |
| 13 | AL359314.1 | 3.86 | 2.96 | 23.0 | 4.44 | 0.000 | 4.2e-01 ↓ | — |
| 14 | MIR3189 | 3.84 | 1.60 | 9.0 | 5.81 | 0.000 | 1.8e-01 ↑worse | — |
| 15 | ERG | 3.83 | 2.48 | 10.0 | 2.98 | 0.000 | 6.8e-01 ↑worse | Act |
| 16 | DLX1 | 3.81 | 2.80 | 23.6 | 5.08 | 0.000 | 3.0e-01 ↓ | — |
| 17 | PAQR6 | 3.74 | 1.95 | 22.2 | 0.46 | 0.000 | 1.5e-02 ↑worse | — |
| 18 | ACSM1 | 3.60 | 2.68 | 14.0 | 4.58 | 0.000 | 9.2e-01 ↓ | — |
| 19 | TRGV9 | 3.57 | 2.52 | 15.2 | 5.07 | 0.000 | 8.8e-01 ↓ | — |
| 20 | CPLX1 | 3.50 | 1.31 | 25.2 | -0.97 | 0.000 | 2.0e-03 ↑worse | — |
| 21 | OR51E2 | 3.42 | 2.31 | 9.7 | 5.52 | 0.000 | 8.9e-01 ↓ | — |
| 22 | ALB | 3.39 | 2.71 | 17.2 | 1.56 | 0.000 | 2.0e-01 ↑worse | — |
| 23 | B4GALNT4 | 3.26 | 1.77 | 21.8 | 0.66 | 0.000 | 1.8e-02 ↑worse | — |
| 24 | ARHGEF38 | 3.08 | 1.35 | 12.1 | 2.12 | 0.000 | 2.3e-02 ↑worse | — |
| 25 | LINC00993 | 3.02 | 3.05 | 20.3 | 3.11 | 0.000 | 2.0e-01 ↓ | — |
| 26 | SLC45A2 | 2.96 | 3.04 | 59.7 | 3.17 | 0.000 | 1.6e-01 ↓ | — |
| 27 | AMACR | 2.95 | 3.05 | 33.7 | 1.56 | 0.000 | 6.5e-01 ↑worse | — |
| 28 | BAIAP2L2 | 2.93 | 1.72 | 14.5 | 0.40 | 0.000 | 2.0e-02 ↑worse | — |
| 29 | TDRD1 | 2.82 | 2.54 | 21.4 | 3.86 | 0.000 | 7.1e-01 ↓ | — |
| 30 | HPN | 2.73 | 2.42 | 18.6 | 3.52 | 0.000 | 7.6e-01 ↑worse | — |
| 31 | EZH2 | 2.70 | 1.07 | 17.0 | 0.66 | 0.000 | 2.7e-02 ↑worse | Act |
| 32 | SNORA73B | 2.68 | 2.00 | 17.6 | 1.69 | 0.000 | 1.1e-01 ↑worse | — |
| 33 | SNORD100 | 2.58 | 1.02 | 9.3 | 3.59 | 0.000 | 5.0e-02 ↑worse | — |
| 34 | AP006748.1 | 2.55 | 2.59 | 30.0 | 3.31 | 0.000 | 6.2e-01 ↓ | — |
| 35 | SNHG25 | 2.55 | 2.08 | 23.9 | 0.53 | 0.000 | 6.9e-02 ↑worse | — |
| 36 | OR51C1P | 2.54 | 2.34 | 19.9 | 2.87 | 0.000 | 5.2e-01 ↑worse | — |
| 37 | ADAM2 | 2.48 | 1.56 | 14.7 | 2.60 | 0.000 | 9.2e-02 ↑worse | — |
| 38 | NBEAP1 | 2.46 | 2.40 | 7.6 | 3.30 | 0.000 | 8.4e-01 ↑worse | — |
| 39 | SCHLAP1 | 2.31 | 2.11 | 8.4 | 3.61 | 0.000 | 6.5e-01 ↑worse | — |
| 40 | SNORD14E | 2.18 | 1.41 | 6.9 | 3.46 | 0.000 | 1.6e-01 ↑worse | — |
| 41 | MYO6 | 2.07 | 1.19 | 10.8 | 2.10 | 0.000 | 4.7e-02 ↑worse | — |
| 42 | ELFN1-AS1 | 2.05 | 2.17 | 16.7 | 3.03 | 0.000 | 6.8e-01 ↑worse | — |
| 43 | MIR25 | 1.99 | 1.19 | 10.1 | 2.93 | 0.000 | 8.7e-02 ↑worse | — |
| 44 | SNHG3 | 1.96 | 1.45 | 20.2 | nan | 0.000 | 2.4e-02 ↑worse | — |
| 45 | SFTPA2 | 1.92 | 1.88 | 4.8 | 4.74 | 0.000 | 4.9e-01 ↓ | — |
| 46 | ST8SIA6-AS1 | 1.92 | 2.29 | 10.8 | 3.63 | 0.000 | 3.0e-01 ↓ | — |
| 47 | SNORD99 | 1.88 | 1.46 | 13.4 | 3.40 | 0.000 | 2.3e-01 ↑worse | — |
| 48 | RPL7P16 | 1.88 | 2.10 | 11.7 | 4.07 | 0.000 | 3.7e-01 ↓ | — |
| 49 | SNORA33 | 1.88 | 1.37 | 13.2 | 4.56 | 0.000 | 3.9e-01 ↑worse | — |
| 50 | SRARP | 1.87 | 2.44 | 15.6 | nan | 0.000 | 2.1e-01 ↑worse | — |