TCGA-KIRC · 50 ranked genes · over-expressed in tumor, supported by survival / mutation / known-driver evidence
| # | Gene | Composite | Over-expr (log2FC)GDC tumor vs normal | −log10 pGDC | Tumor-specificity vs GTExGTEx healthy tissue | Mutation freqGDC SSM | Survival p (hi-expr)GDC clinical | Known driverintOGen |
|---|---|---|---|---|---|---|---|---|
| 1 | FN1 | 15.57 | 1.84 | 20.0 | 3.81 | 0.015 | 5.7e-01 ↑worse | — |
| 2 | C1S | 13.96 | 1.30 | 8.9 | 2.21 | 0.009 | 3.7e-05 ↑worse | — |
| 3 | GAL3ST1 | 11.71 | 2.89 | 50.7 | 4.36 | 0.006 | 6.5e-01 ↓ | — |
| 4 | MAP4K4 | 11.28 | 1.29 | 29.3 | 2.35 | 0.009 | 4.2e-01 ↑worse | — |
| 5 | SAA1 | 11.04 | 4.63 | 6.9 | 6.12 | 0.000 | 3.1e-08 ↑worse | — |
| 6 | SAMHD1 | 10.88 | 1.45 | 23.1 | 1.91 | 0.007 | 5.6e-01 ↓ | LoF |
| 7 | STAT2 | 10.66 | 1.02 | 24.7 | 1.12 | 0.007 | 1.2e-03 ↑worse | — |
| 8 | IL20RB | 9.64 | 3.26 | 45.5 | 4.31 | 0.000 | 1.4e-10 ↑worse | — |
| 9 | CD44 | 9.49 | 1.38 | 16.6 | 2.83 | 0.006 | 7.4e-02 ↑worse | — |
| 10 | FABP7 | 9.01 | 5.51 | 90.1 | 8.19 | 0.000 | 1.4e-01 ↑worse | — |
| 11 | RPLP0 | 8.87 | 1.09 | 29.1 | 1.15 | 0.006 | 4.4e-03 ↑worse | — |
| 12 | FDCSP | 8.43 | 4.94 | 11.0 | 5.23 | 0.000 | 1.4e-04 ↑worse | — |
| 13 | PAEP | 8.33 | 4.08 | 23.2 | 4.12 | 0.000 | 3.3e-07 ↑worse | — |
| 14 | CA9 | 8.27 | 5.59 | 73.9 | 8.41 | 0.000 | 7.7e-03 ↓ | — |
| 15 | SEPTIN4 | 8.21 | 1.18 | 26.3 | nan | 0.007 | 8.5e-01 ↑worse | — |
| 16 | HP | 8.08 | 5.39 | 14.6 | 4.76 | 0.000 | 1.3e-03 ↑worse | — |
| 17 | SNORA73B | 8.06 | 5.00 | 17.3 | 5.12 | 0.000 | 4.9e-04 ↑worse | — |
| 18 | NDUFA4L2 | 7.82 | 5.30 | 73.6 | 7.59 | 0.000 | 8.6e-01 ↑worse | — |
| 19 | SHMT2 | 7.58 | 2.08 | 51.9 | 2.71 | 0.004 | 3.4e-01 ↓ | — |
| 20 | SLC6A3 | 7.23 | 5.47 | 103.4 | 6.96 | 0.000 | 1.3e-02 ↓ | — |
| 21 | SAA2 | 7.18 | 3.15 | 15.7 | 2.96 | 0.000 | 1.9e-08 ↑worse | — |
| 22 | AP1G2 | 6.91 | 1.10 | 31.3 | -2.15 | 0.006 | 3.0e-03 ↑worse | — |
| 23 | NPTX2 | 6.64 | 4.76 | 78.6 | 7.16 | 0.000 | 2.2e-01 ↓ | — |
| 24 | SCARNA5 | 6.48 | 4.80 | 11.7 | 5.28 | 0.000 | 6.0e-02 ↑worse | — |
| 25 | TNFAIP6 | 6.37 | 5.38 | 81.2 | 6.65 | 0.000 | 3.1e-05 ↓ | — |
| 26 | SNORA33 | 6.23 | 1.42 | 24.1 | 3.54 | 0.000 | 5.7e-10 ↑worse | — |
| 27 | PNCK | 6.20 | 4.50 | 85.3 | 5.66 | 0.000 | 8.6e-02 ↑worse | — |
| 28 | IGHGP | 6.16 | 2.64 | 7.8 | 6.45 | 0.000 | 9.7e-05 ↑worse | — |
| 29 | MYEOV | 6.10 | 4.42 | 102.7 | 4.56 | 0.000 | 4.6e-01 ↑worse | Act |
| 30 | ANGPTL4 | 6.09 | 4.85 | 47.3 | 6.23 | 0.000 | 8.8e-02 ↓ | — |
| 31 | C10orf99 | 6.08 | 4.85 | 44.7 | 5.89 | 0.000 | 9.3e-01 ↓ | — |
| 32 | CYP2J2 | 5.95 | 4.97 | 93.8 | 6.53 | 0.000 | 3.3e-04 ↓ | — |
| 33 | IGLV9-49 | 5.89 | 3.95 | 8.4 | 5.56 | 0.000 | 1.5e-02 ↑worse | — |
| 34 | C5orf46 | 5.80 | 4.06 | 68.8 | 5.45 | 0.000 | 2.8e-02 ↑worse | — |
| 35 | IGLV1-40 | 5.79 | 3.54 | 8.1 | 6.78 | 0.000 | 4.4e-02 ↑worse | — |
| 36 | FABP6 | 5.77 | 4.69 | 98.2 | 5.78 | 0.000 | 7.5e-01 ↓ | — |
| 37 | UBE2C | 5.67 | 2.48 | 33.4 | 3.76 | 0.000 | 8.0e-07 ↑worse | — |
| 38 | IGFBP1 | 5.63 | 4.04 | 7.6 | 5.34 | 0.000 | 3.5e-02 ↑worse | — |
| 39 | TTC21B-AS1 | 5.42 | 4.83 | 177.3 | 4.93 | 0.000 | 7.3e-01 ↓ | — |
| 40 | LINC00462 | 5.41 | 4.50 | 94.6 | 5.63 | 0.000 | 6.3e-01 ↓ | — |
| 41 | CCL18 | 5.27 | 4.52 | 66.8 | 5.24 | 0.000 | 8.5e-01 ↑worse | — |
| 42 | IGHG3 | 5.24 | 3.09 | 9.7 | 4.41 | 0.000 | 2.2e-04 ↑worse | — |
| 43 | COL23A1 | 5.18 | 4.68 | 76.9 | 5.65 | 0.000 | 2.7e-03 ↓ | — |
| 44 | CD70 | 5.15 | 3.90 | 64.1 | 6.58 | 0.000 | 3.6e-01 ↓ | — |
| 45 | EGLN3 | 5.12 | 4.21 | 66.9 | 6.20 | 0.000 | 3.4e-02 ↓ | — |
| 46 | IGLV3-19 | 5.01 | 2.81 | 6.9 | 6.37 | 0.000 | 8.9e-03 ↑worse | — |
| 47 | HILPDA | 5.00 | 4.57 | 70.4 | 5.07 | 0.000 | 1.2e-01 ↓ | — |
| 48 | IGHG1 | 4.98 | 2.80 | 7.8 | 6.16 | 0.000 | 6.0e-03 ↑worse | — |
| 49 | SNORD17 | 4.97 | 3.45 | 11.0 | 4.77 | 0.000 | 6.4e-03 ↑worse | — |
| 50 | TREM2 | 4.97 | 3.73 | 49.7 | 5.52 | 0.000 | 1.2e-01 ↑worse | — |