TCGA-KIRC · 50 ranked genes · over-expressed in tumor, supported by survival / mutation / known-driver evidence
| # | Gene | Composite | Over-expr (log2FC)GDC tumor vs normal | −log10 pGDC | Tumor-specificity vs GTExGTEx healthy tissue | Mutation freqGDC SSM | Survival p (hi-expr)GDC clinical | Known driverintOGen |
|---|---|---|---|---|---|---|---|---|
| 1 | FN1 | 15.47 | 1.83 | 20.1 | 3.80 | 0.015 | 6.1e-01 ↑worse | — |
| 2 | C1S | 13.60 | 1.29 | 8.8 | 2.21 | 0.009 | 6.1e-05 ↑worse | — |
| 3 | GAL3ST1 | 11.68 | 2.90 | 51.0 | 4.37 | 0.006 | 4.3e-01 ↓ | — |
| 4 | SAA1 | 11.30 | 4.63 | 6.5 | 6.12 | 0.000 | 6.1e-09 ↑worse | — |
| 5 | MAP4K4 | 11.28 | 1.29 | 29.2 | 2.35 | 0.009 | 3.2e-01 ↑worse | — |
| 6 | STAT2 | 11.19 | 1.02 | 24.6 | 1.12 | 0.007 | 9.8e-05 ↑worse | — |
| 7 | SAMHD1 | 10.77 | 1.44 | 23.0 | 1.90 | 0.007 | 3.3e-01 ↓ | LoF |
| 8 | CD44 | 9.62 | 1.36 | 16.3 | 2.81 | 0.006 | 3.2e-02 ↑worse | — |
| 9 | IL20RB | 9.13 | 3.28 | 45.1 | 4.33 | 0.000 | 3.4e-10 ↑worse | — |
| 10 | FABP7 | 9.00 | 5.51 | 90.7 | 8.19 | 0.000 | 1.8e-01 ↑worse | — |
| 11 | FDCSP | 8.82 | 4.95 | 10.9 | 5.24 | 0.000 | 2.7e-05 ↑worse | — |
| 12 | HP | 8.77 | 5.38 | 13.8 | 4.75 | 0.000 | 8.7e-05 ↑worse | — |
| 13 | RPLP0 | 8.70 | 1.08 | 28.8 | 1.13 | 0.006 | 4.7e-03 ↑worse | — |
| 14 | CA9 | 8.29 | 5.60 | 73.7 | 8.42 | 0.000 | 3.1e-03 ↓ | — |
| 15 | SEPTIN4 | 8.14 | 1.17 | 26.2 | nan | 0.007 | 8.2e-01 ↑worse | — |
| 16 | PAEP | 8.02 | 4.07 | 23.3 | 4.11 | 0.000 | 5.1e-07 ↑worse | — |
| 17 | NDUFA4L2 | 7.92 | 5.30 | 73.4 | 7.59 | 0.000 | 7.7e-01 ↑worse | — |
| 18 | SAA2 | 7.76 | 3.14 | 15.2 | 2.96 | 0.000 | 1.0e-09 ↑worse | — |
| 19 | SHMT2 | 7.59 | 2.09 | 52.1 | 2.71 | 0.004 | 4.0e-01 ↓ | — |
| 20 | SNORA73B | 7.36 | 4.43 | 16.6 | 4.55 | 0.000 | 8.1e-05 ↑worse | — |
| 21 | SLC6A3 | 7.30 | 5.48 | 103.8 | 6.97 | 0.000 | 8.6e-03 ↓ | — |
| 22 | ANGPTL4 | 6.98 | 4.84 | 47.2 | 6.22 | 0.000 | 1.0e-01 ↑worse | — |
| 23 | AP1G2 | 6.86 | 1.09 | 31.4 | -2.16 | 0.006 | 1.9e-03 ↑worse | — |
| 24 | NPTX2 | 6.62 | 4.74 | 78.3 | 7.14 | 0.000 | 1.3e-01 ↓ | — |
| 25 | TNFAIP6 | 6.37 | 5.39 | 81.5 | 6.66 | 0.000 | 6.8e-06 ↓ | — |
| 26 | SCARNA5 | 6.29 | 4.72 | 11.6 | 5.20 | 0.000 | 6.6e-02 ↑worse | — |
| 27 | MYEOV | 6.23 | 4.44 | 101.9 | 4.58 | 0.000 | 3.7e-01 ↑worse | Act |
| 28 | C10orf99 | 6.11 | 4.84 | 45.3 | 5.89 | 0.000 | 7.3e-01 ↓ | — |
| 29 | SNORA33 | 6.06 | 1.37 | 23.6 | 3.49 | 0.000 | 2.5e-10 ↑worse | — |
| 30 | PNCK | 6.06 | 4.47 | 84.8 | 5.63 | 0.000 | 1.2e-01 ↑worse | — |
| 31 | CYP2J2 | 6.01 | 4.96 | 94.0 | 6.52 | 0.000 | 3.0e-04 ↓ | — |
| 32 | C5orf46 | 5.99 | 4.08 | 69.6 | 5.47 | 0.000 | 1.5e-02 ↑worse | — |
| 33 | SNORD17 | 5.97 | 3.85 | 10.8 | 5.16 | 0.000 | 2.8e-03 ↑worse | — |
| 34 | UBE2C | 5.93 | 2.43 | 32.9 | 3.71 | 0.000 | 1.2e-07 ↑worse | — |
| 35 | IGHGP | 5.85 | 2.62 | 7.5 | 6.43 | 0.000 | 1.8e-04 ↑worse | — |
| 36 | FABP6 | 5.78 | 4.65 | 97.3 | 5.75 | 0.000 | 9.8e-01 ↓ | — |
| 37 | IGLV9-49 | 5.75 | 3.94 | 8.0 | 5.55 | 0.000 | 2.2e-02 ↑worse | — |
| 38 | TTC21B-AS1 | 5.58 | 4.87 | 182.8 | 4.97 | 0.000 | 9.8e-01 ↓ | — |
| 39 | IGLV1-40 | 5.56 | 3.50 | 7.8 | 6.75 | 0.000 | 7.9e-02 ↑worse | — |
| 40 | LINC00462 | 5.47 | 4.51 | 94.6 | 5.64 | 0.000 | 5.4e-01 ↓ | — |
| 41 | COL23A1 | 5.37 | 4.70 | 77.2 | 5.67 | 0.000 | 6.8e-03 ↓ | — |
| 42 | IGFBP1 | 5.35 | 4.05 | 7.5 | 5.35 | 0.000 | 9.8e-02 ↑worse | — |
| 43 | CD70 | 5.23 | 3.90 | 64.3 | 6.58 | 0.000 | 4.8e-01 ↓ | — |
| 44 | EGLN3 | 5.23 | 4.21 | 66.8 | 6.20 | 0.000 | 6.4e-02 ↓ | — |
| 45 | CCL18 | 5.21 | 4.50 | 65.8 | 5.22 | 0.000 | 7.6e-01 ↓ | — |
| 46 | TREM2 | 5.18 | 3.71 | 49.6 | 5.50 | 0.000 | 5.1e-02 ↑worse | — |
| 47 | IGKC | 5.14 | 2.31 | 7.7 | 5.50 | 0.000 | 6.4e-05 ↑worse | — |
| 48 | BIRC7 | 5.14 | 4.63 | 97.9 | 4.49 | 0.000 | 5.1e-01 ↑worse | — |
| 49 | ENPP3 | 5.04 | 4.61 | 54.4 | 6.26 | 0.000 | 7.2e-06 ↓ | — |
| 50 | HILPDA | 5.04 | 4.54 | 70.1 | 5.05 | 0.000 | 1.7e-01 ↓ | — |