TCGA-COAD · 50 ranked genes · over-expressed in tumor, supported by survival / mutation / known-driver evidence
| # | Gene | Composite | Over-expr (log2FC)GDC tumor vs normal | −log10 pGDC | Tumor-specificity vs GTExGTEx healthy tissue | Mutation freqGDC SSM | Survival p (hi-expr)GDC clinical | Known driverintOGen |
|---|---|---|---|---|---|---|---|---|
| 1 | COL11A1 | 17.93 | 3.97 | 144.0 | 3.81 | 0.117 | 8.3e-01 ↑worse | — |
| 2 | COL12A1 | 14.30 | 2.12 | 14.9 | 1.26 | 0.132 | 8.9e-01 ↑worse | — |
| 3 | VCAN | 13.92 | 1.59 | 11.7 | 2.07 | 0.121 | 9.3e-01 ↑worse | — |
| 4 | THBS2 | 13.03 | 2.39 | 12.2 | 1.27 | 0.076 | 6.2e-01 ↑worse | — |
| 5 | DMKN | 10.22 | 1.64 | 18.4 | 0.99 | 0.024 | 5.0e-02 ↑worse | — |
| 6 | AMPD2 | 10.10 | 1.28 | 30.3 | 0.34 | 0.056 | 5.9e-01 ↑worse | — |
| 7 | PPBP | 9.92 | 7.12 | 33.6 | 7.51 | 0.000 | 5.3e-01 ↓ | — |
| 8 | NOTUM | 9.83 | 6.43 | 112.5 | 6.48 | 0.000 | 2.1e-01 ↑worse | — |
| 9 | DNMT1 | 9.76 | 1.14 | 16.7 | 0.53 | 0.056 | 8.6e-01 ↑worse | — |
| 10 | ELFN1-AS1 | 9.56 | 4.10 | 81.0 | 4.71 | 0.000 | 2.5e-03 ↑worse | — |
| 11 | MAP4K4 | 9.51 | 1.00 | 16.4 | 0.62 | 0.052 | 7.4e-01 ↑worse | — |
| 12 | RNU5B-1 | 8.76 | 6.53 | 12.1 | 6.62 | 0.000 | — | — |
| 13 | RNU5A-1 | 8.72 | 6.49 | 13.6 | 6.64 | 0.000 | — | — |
| 14 | CST1 | 8.67 | 6.50 | 150.6 | 6.85 | 0.000 | 4.4e-01 ↓ | — |
| 15 | RNU4-2 | 8.55 | 6.69 | 10.5 | 7.13 | 0.000 | 5.0e-02 ↓ | — |
| 16 | MMP7 | 8.30 | 6.14 | 76.0 | 6.63 | 0.000 | 1.0e+00 ↓ | — |
| 17 | RNY1 | 7.98 | 6.01 | 5.5 | 6.39 | 0.000 | — | — |
| 18 | CLDN2 | 7.87 | 5.42 | 37.2 | 7.26 | 0.000 | 9.2e-01 ↓ | — |
| 19 | ETV4 | 7.76 | 5.09 | 54.5 | 6.01 | 0.000 | 7.7e-01 ↓ | Act |
| 20 | TCN1 | 7.58 | 5.59 | 76.3 | 5.89 | 0.000 | 5.9e-01 ↑worse | — |
| 21 | ULBP2 | 7.55 | 2.51 | 99.3 | 2.55 | 0.000 | 4.7e-04 ↑worse | — |
| 22 | SNORA73B | 7.34 | 5.97 | 32.2 | 5.63 | 0.000 | 7.8e-01 ↓ | — |
| 23 | RNU4-1 | 6.85 | 5.90 | 10.3 | 6.50 | 0.000 | 1.4e-02 ↓ | — |
| 24 | CA9 | 6.81 | 5.28 | 65.1 | 5.61 | 0.000 | 7.5e-01 ↑worse | — |
| 25 | KRT23 | 6.71 | 5.50 | 123.2 | 5.70 | 0.000 | 4.8e-01 ↓ | — |
| 26 | SCARNA5 | 6.66 | 5.44 | 14.3 | 5.47 | 0.000 | 9.9e-01 ↑worse | — |
| 27 | AC010378.1 | 6.58 | 2.46 | 58.8 | nan | 0.000 | 1.7e-04 ↑worse | — |
| 28 | COL10A1 | 6.42 | 4.62 | 124.8 | 4.66 | 0.000 | 2.1e-01 ↑worse | — |
| 29 | FOXQ1 | 6.41 | 5.55 | 109.2 | 5.68 | 0.000 | 1.2e-01 ↓ | — |
| 30 | NXPH4 | 6.30 | 3.64 | 63.2 | 3.76 | 0.000 | 2.9e-02 ↑worse | — |
| 31 | RNA5SP141 | 6.24 | 5.23 | 6.5 | 5.23 | 0.000 | — | — |
| 32 | CDH3 | 6.17 | 5.01 | 51.2 | 5.57 | 0.000 | 8.5e-01 ↓ | — |
| 33 | PAEP | 6.12 | 4.41 | 33.1 | 4.44 | 0.000 | 1.9e-01 ↑worse | — |
| 34 | KRTAP5-1 | 6.06 | 1.68 | 25.3 | 1.24 | 0.000 | 3.0e-04 ↑worse | — |
| 35 | CTSH | 6.04 | 1.26 | 17.7 | 0.46 | 0.020 | 4.4e-01 ↓ | — |
| 36 | TNNT1 | 5.96 | 2.87 | 44.2 | 2.58 | 0.000 | 5.5e-03 ↑worse | — |
| 37 | SNORD17 | 5.94 | 4.29 | 43.3 | 5.25 | 0.000 | 3.9e-01 ↑worse | — |
| 38 | CLDN1 | 5.88 | 4.70 | 55.3 | 5.63 | 0.000 | 9.1e-01 ↓ | — |
| 39 | REG3A | 5.82 | 3.57 | 9.4 | 7.92 | 0.000 | 2.7e-01 ↓ | — |
| 40 | DPP7 | 5.69 | 1.23 | 18.8 | 0.65 | 0.000 | 1.5e-04 ↑worse | — |
| 41 | MMP1 | 5.68 | 4.49 | 26.9 | 6.62 | 0.000 | 7.4e-02 ↓ | — |
| 42 | CEMIP | 5.68 | 4.80 | 78.2 | 5.32 | 0.000 | 6.1e-01 ↓ | — |
| 43 | PRSS2 | 5.59 | 4.89 | 11.8 | 4.67 | 0.000 | 8.5e-01 ↑worse | — |
| 44 | SNORA74A | 5.58 | 4.14 | 23.5 | 3.98 | 0.000 | 1.7e-01 ↑worse | — |
| 45 | CPNE7 | 5.51 | 4.55 | 152.2 | 4.36 | 0.000 | 4.4e-01 ↑worse | — |
| 46 | TACSTD2 | 5.51 | 4.64 | 66.8 | 5.21 | 0.000 | 9.3e-01 ↓ | — |
| 47 | SEZ6L2 | 5.49 | 1.44 | 18.1 | 3.11 | 0.000 | 2.0e-03 ↑worse | — |
| 48 | KRT17 | 5.47 | 4.32 | 35.5 | 4.33 | 0.000 | 3.3e-01 ↑worse | — |
| 49 | MMP11 | 5.45 | 4.43 | 92.5 | 4.60 | 0.000 | 4.9e-01 ↑worse | — |
| 50 | RNA5SP355 | 5.40 | 4.78 | 6.5 | 4.78 | 0.000 | — | — |