TCGA-COAD · 50 ranked genes · over-expressed in tumor, supported by survival / mutation / known-driver evidence
| # | Gene | Composite | Over-expr (log2FC)GDC tumor vs normal | −log10 pGDC | Tumor-specificity vs GTExGTEx healthy tissue | Mutation freqGDC SSM | Survival p (hi-expr)GDC clinical | Known driverintOGen |
|---|---|---|---|---|---|---|---|---|
| 1 | COL11A1 | 18.05 | 3.96 | 144.7 | 3.79 | 0.117 | 6.7e-01 ↑worse | — |
| 2 | COL12A1 | 14.49 | 2.13 | 15.0 | 1.27 | 0.132 | 7.3e-01 ↑worse | — |
| 3 | VCAN | 14.16 | 1.63 | 11.7 | 2.11 | 0.121 | 7.6e-01 ↑worse | — |
| 4 | THBS2 | 13.22 | 2.37 | 12.2 | 1.25 | 0.076 | 4.8e-01 ↑worse | — |
| 5 | DMKN | 10.23 | 1.64 | 18.4 | 0.99 | 0.024 | 5.0e-02 ↑worse | — |
| 6 | AMPD2 | 9.93 | 1.28 | 30.2 | 0.34 | 0.056 | 7.3e-01 ↑worse | — |
| 7 | PPBP | 9.89 | 7.12 | 33.4 | 7.51 | 0.000 | 6.2e-01 ↓ | — |
| 8 | DNMT1 | 9.77 | 1.14 | 16.7 | 0.53 | 0.056 | 8.5e-01 ↑worse | — |
| 9 | NOTUM | 9.77 | 6.42 | 112.3 | 6.47 | 0.000 | 2.1e-01 ↑worse | — |
| 10 | MAP4K4 | 9.51 | 1.00 | 16.4 | 0.61 | 0.052 | 7.4e-01 ↑worse | — |
| 11 | ELFN1-AS1 | 9.48 | 4.10 | 81.1 | 4.71 | 0.000 | 2.7e-03 ↑worse | — |
| 12 | RNU5B-1 | 8.92 | 6.65 | 12.2 | 6.73 | 0.000 | — | — |
| 13 | RNU5A-1 | 8.91 | 6.62 | 13.7 | 6.77 | 0.000 | — | — |
| 14 | RNY1 | 8.80 | 6.48 | 5.7 | 6.85 | 0.000 | — | — |
| 15 | RNU4-2 | 8.65 | 6.78 | 10.7 | 7.22 | 0.000 | 4.8e-02 ↓ | — |
| 16 | CST1 | 8.61 | 6.50 | 150.7 | 6.85 | 0.000 | 4.4e-01 ↓ | — |
| 17 | MMP7 | 8.25 | 6.14 | 76.0 | 6.63 | 0.000 | 1.0e+00 ↓ | — |
| 18 | ETV4 | 8.01 | 5.09 | 54.5 | 6.01 | 0.000 | 7.6e-01 ↑worse | Act |
| 19 | CLDN2 | 7.81 | 5.42 | 37.2 | 7.26 | 0.000 | 9.1e-01 ↓ | — |
| 20 | TCN1 | 7.51 | 5.58 | 76.2 | 5.88 | 0.000 | 5.9e-01 ↑worse | — |
| 21 | ULBP2 | 7.49 | 2.47 | 100.1 | 2.50 | 0.000 | 4.7e-04 ↑worse | — |
| 22 | SNORA73B | 7.37 | 6.05 | 32.7 | 5.71 | 0.000 | 6.1e-01 ↓ | — |
| 23 | SCARNA5 | 6.82 | 5.54 | 14.4 | 5.57 | 0.000 | 9.8e-01 ↑worse | — |
| 24 | COL10A1 | 6.69 | 4.62 | 125.1 | 4.66 | 0.000 | 1.5e-01 ↑worse | — |
| 25 | KRT23 | 6.59 | 5.51 | 123.4 | 5.70 | 0.000 | 3.4e-01 ↓ | — |
| 26 | RNU4-1 | 6.51 | 5.75 | 10.5 | 6.35 | 0.000 | 1.4e-02 ↓ | — |
| 27 | CA9 | 6.46 | 5.27 | 64.9 | 5.61 | 0.000 | 7.8e-01 ↓ | — |
| 28 | FOXQ1 | 6.36 | 5.55 | 108.8 | 5.68 | 0.000 | 1.2e-01 ↓ | — |
| 29 | NXPH4 | 6.33 | 3.66 | 62.8 | 3.78 | 0.000 | 2.9e-02 ↑worse | — |
| 30 | AC010378.1 | 6.23 | 2.46 | 58.6 | nan | 0.000 | 2.7e-04 ↑worse | — |
| 31 | RNA5SP141 | 6.21 | 5.24 | 6.8 | 5.24 | 0.000 | — | — |
| 32 | CDH3 | 6.13 | 5.00 | 50.9 | 5.56 | 0.000 | 8.7e-01 ↓ | — |
| 33 | PAEP | 6.09 | 4.40 | 33.1 | 4.44 | 0.000 | 1.9e-01 ↑worse | — |
| 34 | SNORD17 | 6.07 | 4.38 | 43.7 | 5.33 | 0.000 | 3.9e-01 ↑worse | — |
| 35 | CTSH | 6.05 | 1.26 | 17.7 | 0.46 | 0.020 | 4.4e-01 ↓ | — |
| 36 | INHBA | 5.87 | 3.81 | 114.8 | 3.89 | 0.000 | 6.8e-02 ↑worse | — |
| 37 | CLDN1 | 5.83 | 4.70 | 55.3 | 5.63 | 0.000 | 9.1e-01 ↓ | — |
| 38 | SNORA74A | 5.77 | 4.25 | 23.9 | 4.09 | 0.000 | 1.7e-01 ↑worse | — |
| 39 | REG3A | 5.75 | 3.56 | 9.3 | 7.92 | 0.000 | 2.5e-01 ↓ | — |
| 40 | DPP7 | 5.68 | 1.23 | 18.8 | 0.64 | 0.000 | 1.6e-04 ↑worse | — |
| 41 | CEMIP | 5.64 | 4.80 | 78.1 | 5.32 | 0.000 | 6.2e-01 ↓ | — |
| 42 | MMP1 | 5.63 | 4.49 | 26.9 | 6.62 | 0.000 | 7.4e-02 ↓ | — |
| 43 | PRSS2 | 5.55 | 4.89 | 11.8 | 4.67 | 0.000 | 8.5e-01 ↑worse | — |
| 44 | SCARNA6 | 5.54 | 3.85 | 10.9 | 4.68 | 0.000 | 2.0e-01 ↑worse | — |
| 45 | CPNE7 | 5.53 | 4.55 | 152.4 | 4.36 | 0.000 | 4.2e-01 ↑worse | — |
| 46 | SEZ6L2 | 5.48 | 1.42 | 18.0 | 3.10 | 0.000 | 2.0e-03 ↑worse | — |
| 47 | TACSTD2 | 5.47 | 4.64 | 66.8 | 5.20 | 0.000 | 9.5e-01 ↓ | — |
| 48 | MACC1 | 5.41 | 2.32 | 28.6 | 3.56 | 0.000 | 4.6e-02 ↑worse | LoF |
| 49 | CDKN2A | 5.40 | 2.22 | 54.4 | 2.38 | 0.000 | 1.5e-02 ↑worse | Act |
| 50 | KRT17 | 5.40 | 4.32 | 35.5 | 4.33 | 0.000 | 3.4e-01 ↑worse | — |