TCGA-BRCA · 50 ranked genes · over-expressed in tumor, supported by survival / mutation / known-driver evidence
| # | Gene | Composite | Over-expr (log2FC)GDC tumor vs normal | −log10 pGDC | Tumor-specificity vs GTExGTEx healthy tissue | Mutation freqGDC SSM | Survival p (hi-expr)GDC clinical | Known driverintOGen |
|---|---|---|---|---|---|---|---|---|
| 1 | GATA3 | 23.05 | 1.79 | 14.1 | 3.91 | 0.098 | 8.6e-01 ↑worse | Act |
| 2 | ERBB2 | 15.66 | 1.85 | 12.7 | 3.07 | 0.021 | 9.8e-01 ↑worse | Act |
| 3 | FN1 | 15.05 | 2.92 | 53.2 | 3.52 | 0.016 | 9.9e-01 ↑worse | — |
| 4 | CLEC3A | 10.85 | 5.42 | 12.0 | 8.19 | 0.000 | 4.3e-02 ↑worse | — |
| 5 | COL10A1 | 9.01 | 6.14 | 196.7 | 7.10 | 0.000 | 4.3e-01 ↑worse | — |
| 6 | MMP11 | 8.31 | 5.93 | 168.8 | 6.44 | 0.000 | 4.2e-01 ↑worse | — |
| 7 | CASP14 | 7.94 | 4.83 | 23.5 | 5.13 | 0.000 | 5.1e-02 ↑worse | — |
| 8 | COL11A1 | 7.81 | 5.22 | 142.2 | 6.12 | 0.000 | 2.1e-01 ↑worse | — |
| 9 | CST1 | 7.32 | 5.27 | 112.0 | 5.87 | 0.000 | 3.3e-01 ↑worse | — |
| 10 | CST5 | 7.08 | 5.79 | 31.5 | 6.08 | 0.000 | 8.7e-01 ↓ | — |
| 11 | MMP1 | 6.82 | 5.07 | 95.4 | 5.62 | 0.000 | 3.6e-01 ↑worse | — |
| 12 | CEACAM6 | 6.73 | 4.05 | 30.4 | 7.49 | 0.000 | 3.6e-01 ↑worse | — |
| 13 | LINC01614 | 6.59 | 4.22 | 141.8 | 5.02 | 0.000 | 8.8e-02 ↑worse | — |
| 14 | CGA | 6.57 | 5.56 | 25.2 | 5.66 | 0.000 | 9.8e-01 ↑worse | — |
| 15 | S100P | 6.56 | 4.65 | 57.0 | 7.44 | 0.000 | 9.8e-01 ↑worse | — |
| 16 | SMR3B | 6.53 | 4.71 | 5.9 | 7.28 | 0.000 | — | — |
| 17 | PRAME | 6.34 | 3.63 | 23.6 | 4.58 | 0.000 | 3.7e-02 ↑worse | — |
| 18 | TPD52 | 5.96 | 1.76 | 28.2 | 3.35 | 0.000 | 1.6e-03 ↑worse | — |
| 19 | PCSK1 | 5.91 | 5.45 | 8.3 | 4.99 | 0.000 | 8.1e-01 ↓ | — |
| 20 | MAL2 | 5.85 | 1.59 | 28.0 | 7.91 | 0.000 | 3.9e-02 ↑worse | — |
| 21 | SLC7A5 | 5.70 | 2.41 | 31.0 | 3.30 | 0.000 | 5.1e-03 ↑worse | — |
| 22 | PSPHP1 | 5.59 | 1.50 | 6.7 | 5.65 | 0.000 | 8.7e-03 ↑worse | — |
| 23 | CD24 | 5.50 | 1.42 | 7.4 | 4.03 | 0.000 | 2.6e-03 ↑worse | — |
| 24 | CST2 | 5.43 | 3.61 | 96.8 | 4.18 | 0.000 | 7.3e-02 ↑worse | — |
| 25 | CST4 | 5.40 | 4.70 | 63.0 | 4.80 | 0.000 | 5.7e-01 ↑worse | — |
| 26 | SDC1 | 5.31 | 1.76 | 18.4 | 4.84 | 0.000 | 9.7e-03 ↑worse | — |
| 27 | SLC30A8 | 5.26 | 4.74 | 20.1 | 5.49 | 0.000 | 6.2e-01 ↓ | — |
| 28 | S100A7 | 5.24 | 3.26 | 11.6 | 8.74 | 0.000 | 2.4e-01 ↓ | — |
| 29 | PVALB | 5.21 | 4.33 | 20.3 | 5.54 | 0.000 | 7.1e-01 ↑worse | — |
| 30 | CYP2B7P | 5.17 | 3.81 | 25.9 | 6.52 | 0.000 | 7.2e-01 ↑worse | — |
| 31 | LRRC15 | 5.13 | 3.66 | 69.6 | 5.97 | 0.000 | 4.1e-01 ↑worse | — |
| 32 | CILP2 | 5.09 | 2.68 | 106.7 | 3.31 | 0.000 | 1.5e-02 ↑worse | — |
| 33 | ORM1 | 5.06 | 3.99 | 29.7 | 3.75 | 0.000 | 1.4e-01 ↑worse | — |
| 34 | NKAIN1 | 5.05 | 3.82 | 52.1 | 5.70 | 0.000 | 4.6e-01 ↑worse | — |
| 35 | SYT13 | 5.02 | 4.36 | 46.1 | 5.63 | 0.000 | 9.7e-01 ↑worse | — |
| 36 | SPDYC | 4.98 | 4.01 | 29.9 | 4.16 | 0.000 | 2.1e-01 ↑worse | — |
| 37 | CRISP3 | 4.97 | 3.97 | 4.5 | 6.95 | 0.000 | 2.4e-01 ↓ | — |
| 38 | HMGB3 | 4.97 | 2.34 | 70.2 | 3.91 | 0.000 | 1.6e-02 ↑worse | — |
| 39 | DSCAM-AS1 | 4.95 | 4.50 | 46.9 | 5.20 | 0.000 | 9.5e-01 ↑worse | — |
| 40 | MMP13 | 4.94 | 4.46 | 112.3 | 5.18 | 0.000 | 8.8e-01 ↑worse | — |
| 41 | BMPR1B | 4.93 | 4.05 | 22.6 | 6.35 | 0.000 | 6.0e-01 ↓ | — |
| 42 | CYP2A6 | 4.85 | 3.99 | 5.2 | 6.24 | 0.000 | 7.8e-01 ↓ | — |
| 43 | CXCL10 | 4.83 | 3.30 | 50.3 | 6.44 | 0.000 | 4.8e-01 ↑worse | — |
| 44 | IGHG1 | 4.79 | 2.77 | 13.8 | 7.34 | 0.000 | 4.5e-01 ↑worse | — |
| 45 | TOP2A | 4.77 | 3.24 | 58.0 | 5.71 | 0.000 | 8.4e-01 ↓ | Act |
| 46 | TFF1 | 4.76 | 2.74 | 7.7 | 10.17 | 0.000 | 1.5e-02 ↓ | — |
| 47 | TPX2 | 4.69 | 3.30 | 82.8 | 5.06 | 0.000 | 2.0e-01 ↑worse | — |
| 48 | SNORA73B | 4.57 | 4.96 | 11.3 | 5.14 | 0.000 | 3.8e-02 ↓ | — |
| 49 | KCNJ3 | 4.57 | 4.42 | 22.5 | 5.56 | 0.000 | 1.8e-01 ↓ | — |
| 50 | NDUFAF6 | 4.51 | 1.19 | 50.4 | 1.97 | 0.000 | 1.3e-03 ↑worse | — |