TCGA-BRCA · 50 ranked genes · over-expressed in tumor, supported by survival / mutation / known-driver evidence
| # | Gene | Composite | Over-expr (log2FC)GDC tumor vs normal | −log10 pGDC | Tumor-specificity vs GTExGTEx healthy tissue | Mutation freqGDC SSM | Survival p (hi-expr)GDC clinical | Known driverintOGen |
|---|---|---|---|---|---|---|---|---|
| 1 | GATA3 | 22.59 | 1.74 | 13.1 | 3.86 | 0.098 | 6.6e-01 ↓ | Act |
| 2 | ERBB2 | 16.29 | 1.79 | 11.5 | 3.01 | 0.021 | 4.2e-01 ↑worse | Act |
| 3 | FN1 | 15.41 | 2.96 | 53.5 | 3.55 | 0.016 | 6.7e-01 ↑worse | — |
| 4 | CLEC3A | 10.16 | 5.34 | 11.8 | 8.12 | 0.000 | 8.7e-02 ↑worse | — |
| 5 | COL10A1 | 8.46 | 6.16 | 196.4 | 7.12 | 0.000 | 7.5e-01 ↑worse | — |
| 6 | MMP11 | 8.22 | 5.94 | 169.3 | 6.45 | 0.000 | 4.6e-01 ↑worse | — |
| 7 | CST5 | 7.32 | 6.02 | 29.5 | 6.31 | 0.000 | 5.7e-01 ↓ | — |
| 8 | FDCSP | 7.29 | 2.76 | 10.2 | 8.46 | 0.000 | 7.2e-02 ↑worse | — |
| 9 | S100P | 6.60 | 4.63 | 59.4 | 7.42 | 0.000 | 8.5e-01 ↑worse | — |
| 10 | COL11A1 | 6.55 | 5.28 | 142.6 | 6.18 | 0.000 | 9.1e-01 ↑worse | — |
| 11 | CXCL9 | 6.24 | 2.98 | 34.9 | 5.91 | 0.000 | 5.1e-02 ↑worse | — |
| 12 | SMR3B | 6.20 | 4.58 | 7.3 | 7.15 | 0.000 | — | — |
| 13 | IBSP | 6.06 | 4.47 | 117.8 | 4.56 | 0.000 | 1.8e-01 ↑worse | — |
| 14 | SLC30A8 | 5.97 | 4.78 | 20.2 | 5.53 | 0.000 | 5.6e-01 ↑worse | — |
| 15 | CGA | 5.92 | 5.45 | 24.6 | 5.55 | 0.000 | 3.0e-01 ↓ | — |
| 16 | MMP1 | 5.91 | 4.99 | 93.8 | 5.54 | 0.000 | 7.8e-01 ↑worse | — |
| 17 | CEACAM6 | 5.90 | 4.03 | 29.8 | 7.47 | 0.000 | 8.3e-01 ↑worse | — |
| 18 | TOP2A | 5.67 | 3.30 | 57.7 | 5.77 | 0.000 | 4.4e-01 ↑worse | Act |
| 19 | CASP14 | 5.56 | 4.88 | 24.7 | 5.18 | 0.000 | 7.7e-01 ↑worse | — |
| 20 | IGHG1 | 5.56 | 2.87 | 13.8 | 7.44 | 0.000 | 2.5e-01 ↑worse | — |
| 21 | NXPH4 | 5.53 | 1.87 | 22.1 | 2.80 | 0.000 | 3.0e-03 ↑worse | — |
| 22 | CD24 | 5.52 | 1.31 | 7.0 | 3.92 | 0.000 | 3.1e-03 ↑worse | — |
| 23 | CST2 | 5.52 | 4.10 | 97.3 | 4.67 | 0.000 | 2.0e-01 ↑worse | — |
| 24 | CST4 | 5.49 | 4.86 | 61.4 | 4.97 | 0.000 | 6.9e-01 ↑worse | — |
| 25 | SDC1 | 5.48 | 1.75 | 18.4 | 4.82 | 0.000 | 1.1e-02 ↑worse | — |
| 26 | CST1 | 5.42 | 5.34 | 118.1 | 5.94 | 0.000 | 3.5e-02 ↓ | — |
| 27 | MMP12 | 5.34 | 2.22 | 11.1 | 3.89 | 0.000 | 1.2e-02 ↑worse | — |
| 28 | DSCAM-AS1 | 5.18 | 4.51 | 43.8 | 5.20 | 0.000 | 7.0e-01 ↑worse | — |
| 29 | PXDNL | 5.16 | 1.46 | 4.2 | 2.40 | 0.000 | 2.0e-03 ↑worse | — |
| 30 | TFF1 | 5.11 | 2.85 | 8.3 | 10.28 | 0.000 | 4.0e-02 ↓ | — |
| 31 | PCSK1 | 5.11 | 5.18 | 8.0 | 4.73 | 0.000 | 3.8e-01 ↓ | — |
| 32 | IGHGP | 5.10 | 2.40 | 11.6 | 7.07 | 0.000 | 1.7e-01 ↑worse | — |
| 33 | S100A7 | 5.07 | 3.04 | 11.9 | 8.52 | 0.000 | 8.0e-01 ↓ | — |
| 34 | MMP13 | 5.06 | 4.52 | 113.2 | 5.24 | 0.000 | 8.3e-01 ↑worse | — |
| 35 | HLA-DQA2 | 5.01 | 1.08 | 5.4 | 2.99 | 0.000 | 2.1e-03 ↑worse | — |
| 36 | PVALB | 5.00 | 4.43 | 21.1 | 5.63 | 0.000 | 9.4e-01 ↓ | — |
| 37 | IL4I1 | 4.86 | 2.21 | 51.9 | 3.21 | 0.000 | 1.2e-02 ↑worse | — |
| 38 | CEACAM5 | 4.86 | 3.77 | 38.7 | 5.50 | 0.000 | 4.6e-01 ↑worse | — |
| 39 | SPDYC | 4.83 | 4.46 | 28.4 | 4.61 | 0.000 | 6.4e-01 ↑worse | — |
| 40 | MAL2 | 4.80 | 1.51 | 26.3 | 7.83 | 0.000 | 1.2e-01 ↑worse | — |
| 41 | BMPR1B | 4.77 | 3.84 | 20.9 | 6.15 | 0.000 | 8.5e-01 ↑worse | — |
| 42 | KCNJ3 | 4.77 | 4.38 | 25.2 | 5.52 | 0.000 | 6.6e-01 ↓ | — |
| 43 | SYT1 | 4.74 | 2.55 | 10.5 | 3.58 | 0.000 | 2.8e-02 ↑worse | — |
| 44 | TRH | 4.73 | 4.54 | 5.6 | 5.60 | 0.000 | 2.4e-01 ↓ | — |
| 45 | CBLN2 | 4.66 | 3.49 | 29.0 | 3.65 | 0.000 | 1.1e-01 ↑worse | — |
| 46 | CXCL10 | 4.63 | 3.37 | 49.3 | 6.51 | 0.000 | 6.8e-01 ↑worse | — |
| 47 | LINC01614 | 4.61 | 4.26 | 143.7 | 5.06 | 0.000 | 8.4e-01 ↑worse | — |
| 48 | RN7SL3 | 4.55 | 3.94 | 16.2 | 4.44 | 0.000 | 3.8e-01 ↑worse | — |
| 49 | UBE2C | 4.53 | 3.88 | 74.6 | 5.93 | 0.000 | 1.0e+00 ↑worse | — |
| 50 | LRRC15 | 4.52 | 3.70 | 70.1 | 6.01 | 0.000 | 8.4e-01 ↑worse | — |